Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.

Our Science

Be Bio is a leader in developing engineered B cells as a new category of cellular medicines. B cells are one of the most unique and versatile populations of cells in the body, playing a key role in humoral immunity and in modulating immune cell behavior in tumors and chronically inflamed tissues. They are among the human body’s most prolific secreted protein factories, they traffic to tissues in a targetable fashion, and they can engraft in niches for as long as decades.

Our goal is to harness B cells’ rich biology and intrinsic drug-like properties by precisely engineering them to forge a new category of cell therapy. B cells address some of the major hurdles of cell & gene therapies today, such as inability to redose, unpredictable PK/PD, and the need to treat patients with toxic chemotherapy regimens prior to administering the cell therapy. B cell medicines are designed to be durable, re-dosable and can be administered without toxic conditioning, creating new avenues to halt or reverse severe diseases like cancer, autoimmune conditions, infectious disease, and enzyme deficiencies. Founded by Longwood Fund and B cell engineering pioneers David Rawlings, MD and Richard James, PhD, Be Bio is re-imagining medicine based on the power of B cell therapy.


Our Team

Management and Board

Joanne Smith-FarrellPhD
Chief Executive Officer & Director
Lea Hachigian, PhD
Aleks Radovic-Moreno, PhD
Co-founder and Director
Josh Resnick, MD, MBA
Rick MorganPhD
Chief Scientific Officer
David SteinbergMBA
Co-founder and Director
Jason RhodesMBA
Dan JanneyMBA

Scientific Advisory Board

David Rawlings, MD
Shiv Pillai, MD, PhD
Richard James, PhD
Frances Eun-Hyung Lee, MD
Jason Cyster, PhD



Careers at Be Bio

Here at Be Bio, we are committed to a diversity of ideas, interests, and backgrounds. This is reflected in our leadership team and growing "family" of inspired individuals who are committed to supporting each other, as well as the people around the world who will one day benefit from our therapies! 

Be Bio is looking for motivated individuals to join its growing team.
Please click here to see our current openings or e-mail for more information.


October 22, 2020
Boston Business Journal
Longwood, Atlas Venture inject $52M into cell therapy startup

Contact Us

One Kendall Sq. 
B200, Suite 001

Cambridge, MA 02139

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